Assistant Professor
Role and establishment of histone modifications
Chromatin structure
Selected Publications
Peterson, C.L. and Shogren-Knaak, M.A.
(2006). Mechanistic role of H4-K16 acetylation. Cell Science.
In press.
Shogren-Knaak, M.A., Ishi, H. and Peterson, C.L. (2006) Histone H4-K16
acetylation controls chromatin structure and protein interactions. Science.
311, 844-847.
Shogren-Knaak, M.A., Fry, C.J., and Peterson, C.L. (2004) Histone H3
Amino-terminal phosphorylation and acetylation: Synergistic or independent
transcriptional regulatory marks? Cold Spring Habor Symposium on Quantitative
Biology. 69, 1-8.
Shogren-Knaak, M.A., and Peterson, C.L. (2004) Creating designer histones
with native chemical ligation. Methods Enzymol. 375, 62-76.
Shogren-Knaak, M.A., Fry, C.J., and Peterson, C.L. (2003) A native ligation
strategy for deciphering nucleosomal histone modifications. J. Biol.
Chem. 278, 15744-15748.
Shogren-Knaak, M.A., Alaimo, P.J., and Shokat, K.M. (2001) Recent advances
in chemical approaches to the study of biological systems. Annu.
Rev. Cell Biol. 17, 405-433.
Alaimo, P.J., Shogren-Knaak, M.A., and Shokat, K.M. (2001) Chemical
genetic approaches for the elucidation of signaling pathways. Curr.
Opin. Chem. Biol. 5, 360-367.
Shogren-Knaak, M.A., McDonnel, K.A., and Imperiali, B. (2000) a -Chloroacetyl
capping of peptides: A N-terminal capping strategy suitable for edman
sequencing. Tetrahedron Lett. 41, 827-829.
Shogren-Knaak, M.A., and Imperiali, B. (1999) Modulating pyridoxamine
mediated transamination through a bba-motif peptide scaffold. Bioorg.
Med Chem. 7, 1993-2002.
Imperiali, B., McDonnell, K.A., and Shogren-Knaak, M.A. (1999) Design
and construction of novel peptides and proteins by tailored incorporation
of coenzyme funcationality. Topics in Current Chemistry. Volume:
Implementation and Redesign of Catalytic Functions in Bipolymers.Springer-Verlag,
Berlin. 1-38.
Shogren-Knaak, M.A., and Imperiali, B. (1998) A reversible affinity
tag for the purification of N-glycolyl capped peptides.Tetrahedron
Lett. 39:(45), 8241-8244.
