Assistant Professor
Joint appointment with Physics & Astronomy
Structural and mechanistic aspects of membrane transport
X-ray crystallography of membrane proteins
Biophysics
Selected Publications
Yu, E.W., McDermott,
G., Koshland, D.E., Jr. and Nikaido, H. (2004) Mechanism of drug transport
in the AcrB multidrug efflux pump. Submitted for publication.
Yu, E.W., McDermott, G., Zgurskaya, H.I., Nikaido, H. and Koshland,
D.E., Jr. (2003) Structural basis of multiple drug-binding capacity
of the AcrB multidrug efflux pump. Science 300, 976.
Yu, E.W., Aires, J.R. and Nikaido, H. (2003) AcrB multidrug efflux pump
of Escherichia coli: A composite substrate-binding cavity of an exceptional
flexibility generates its extremely wide substrate specificity. J.
Bacteriol. 185, 5657.
Yu, E.W. and Koshland, D.E., Jr. (2001) Propagating conformational changes
over long (and short) distances in proteins. Proc. Nat. Acad. Sci. USA
98, 9517.
