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PRODID:-//Iowa State University CALS LAS Web Team//sites.iastate.edu//EN
BEGIN:VEVENT
UID:20231102T204000-573-www.bbmb.iastate.edu
DTSTART:20231102T204000Z
SEQUENCE:0
TRANSP:OPAQUE
DTEND:20231102T214000Z
SUMMARY:BBMB Seminar - Michele Di Pierro\, Professor\, Northwestern Univers
 ity\; Landscapes of Genomic Architecture Across Evolution
CLASS:PUBLIC
DESCRIPTION:Abstract: The human genome is composed of 46 DNA molecules — 
 the chromosomes — with a combined length of about two meters. Chromosome
 s are stored in the cell nucleus in a very organized fashion that is speci
 fic to the cell type and phase of life\; this three-dimensional architectu
 re is a key element of transcriptional regulation\, and its disruption oft
 en leads to disease. What is the physical mechanism leading to genome arch
 itecture? If the DNA contained in every human cell is identical\, where is
  the blueprint of such architecture stored? In this talk\, I will demonstr
 ate how the architecture of interphase chromosomes is encoded in the one-d
 imensional sequence of epigenetic markings much as three-dimensional prote
 in structures are determined by their one-dimensional sequence of amino ac
 ids.\n\nMore information at: https://www.bbmb.iastate.edu/event/2023/bbmb-
 seminar-michele-di-pierro-professor-northwestern-university-landscapes-gen
 omic
DTSTAMP:20261014T193640Z
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