Cobalt ferrite nanocrystals: out-performing magnetotactic bacteria


Publication Type:

Journal Article


ACSNano, Volume 1, Number 3, p.228-33 (2007)


1936-086X (Electronic)<br/>1936-0851 (Linking)

Accession Number:



Bacterial Proteins/metabolism, Cobalt/*chemistry, Diffusion, Ferric Compounds/*chemical synthesis/chemistry, Magnetics, Magnetospirillum/*metabolism, Metal Nanoparticles/*chemistry, Polymers/chemistry, Temperature, Water/chemistry, X-Ray Diffraction


<p>Magnetotactic bacteria produce exquisitely ordered chains of uniform magnetite (Fe(3)O(4)) nanocrystals, and the use of the bacterial mms6 protein allows for the shape-selective synthesis of Fe(3)O(4) nanocrystals. Cobalt ferrite (CoFe(2)O(4)) nanoparticles, on the other hand, are not known to occur in living organisms. Here we report on the use of the recombinant mms6 protein in a templated synthesis of CoFe(2)O(4) nanocrystals in vitro. We have covalently attached the full-length mms6 protein and a synthetic C-terminal domain of mms6 protein to self-assembling polymers in order to template hierarchical CoFe(2)O(4) nanostructures. This new synthesis pathway enables facile room-temperature shape-specific synthesis of complex magnetic crystalline nanomaterials with particle sizes in the range of 40-100 nm that are difficult to produce using conventional techniques.</p>


Prozorov, Tanya<br/>Palo, Pierre<br/>Wang, Lijun<br/>Nilsen-Hamilton, Marit<br/>Jones, DeAnna<br/>Orr, Daniel<br/>Mallapragada, Surya K<br/>Narasimhan, Balaji<br/>Canfield, Paul C<br/>Prozorov, Ruslan<br/>ACS Nano. 2007 Oct;1(3):228-33. doi: 10.1021/nn700194h.