Export 91 results:
N. Kitaoka, Lu, X., Yang, B., and Peters, R. J., The application of synthetic biology to elucidation of plant mono-, sesqui-, and diterpenoid metabolism, Mol Plant, vol. 8, pp. 6-16, 2015.
Y. Matsuba, Zi, J., Jones, A. D., Peters, R. J., and Pichersky, E., Biosynthesis of the Diterpenoid Lycosantalonol via Nerylneryl Diphosphate in Solanum lycopersicum, PLoS One, vol. 10, p. e0119302, 2015.
S. Mafu, Potter, K. C., Hillwig, M. L., Schulte, S., Criswell, J., and Peters, R. J., Efficient heterocyclisation by (di)terpene synthases, Chem Commun (Camb), vol. 51, no. 70, pp. 13485-7, 2015.
X. Lu, Hershey, D. M., Wang, L., Bogdanove, A. J., and Peters, R. J., An ent-kaurene-derived diterpenoid virulence factor from Xanthomonas oryzae pv. oryzicola, New Phytol, vol. 206, pp. 295-302, 2015.
Z. Xu, Peters, R. J., Weirather, J., Luo, H., Liao, B., Zhang, X., Zhu, Y., Ji, A., Zhang, B., Hu, S., Au, K. F., Song, J., and Chen, S., Full-length transcriptome sequences and splice variants obtained by a combination of sequencing platforms applied to different root tissues of Salvia miltiorrhiza and tanshinone biosynthesis, Plant J, vol. 82, pp. 951-61, 2015.
G. Cui, Duan, L., Jin, B., Qian, J., Xue, Z., Shen, G., Snyder, J. H., Song, J., Chen, S., Huang, L., Peters, R. J., and Qi, X., Funcation divergence of diterpene synthases in the medicinal plant Salvia miltiorrhiza Bunge, Plant Physiol, vol. 169, pp. 1607-1618, 2015.
A. M. Boutanaev, Moses, T., Zi, J., Nelson, D. R., Mugford, S. T., Peters, R. J., and Osbourn, A., Investigation of terpene diversification across multiple sequenced plant genomes, Proc Natl Acad Sci U S A, vol. 112, pp. E81-8, 2015.
A. T. Klein, Yagnik, G. B., Hohenstein, J. D., Ji, Z., Zi, J., Reichert, M. D., MacIntosh, G. C., Yang, B., Peters, R. J., Vela, J., and Lee, Y. J., Investigation of the Chemical Interface in the Soybean-Aphid and Rice-Bacteria Interactions Using MALDI-Mass Spectrometry Imaging, Anal Chem, vol. 87, no. 10, pp. 5294-5301, 2015.
N. Kitaoka, Wu, Y., Xu, M., and Peters, R. J., Optimization of recombinant expression enables discovery of novel cytochrome P450 activity in rice diterpenoid biosynthesis, Appl Microbiol Biotechnol, vol. 99, no. 18, 2015.
M. Köksal, Potter, K., Peters, R. J., and Christianson, D. W., 1.55 Å-resolution structure of ent-copalyl diphosphate synthase and exploration of general acid function by site-directed mutagenesis, Biochimica et Biophysica Acta (BBA), vol. 1840, no. 1, pp. 184-190, 2014.
A. J. Jackson, Hershey, D. M., Chesnut, T., Xu, M., and Peters, R. J., Biochemical characterization of the castor bean ent-kaurene synthase(-like) family supports quantum chemical view of diterpene cyclization, Phytochemistry, vol. 103, pp. 13-21, 2014.
E. A. Schmelz, Huffaker, A., Sims, J. W., Christensen, S. A., Lu, X., Okada, K., and Peters, R. J., Biosynthesis, elicitation and roles of monocot terpenoid phytoalexins, The Plant Journal, vol. 79, no. 4, pp. 659-678, 2014.
J. Zi, Matsuba, Y., Hong, Y. J., Jackson, A. J., Tantillo, D. J., Pichersky, E., and Peters, R. J., Biosynthesis of lycosantalonol, a cis-prenyl derived diterpenoid, J Am Chem Soc, vol. 136, pp. 16951-3, 2014.
M. Xu, Hillwig, M. L., Lane, A. L., Tiernan, M. S., Moore, B. S., and Peters, R. J., Characterization of an Orphan Diterpenoid Biosynthetic Operon from Salinispora arenicola, Journal of natural products, vol. 77, no. 9, pp. 2144-2147, 2014.
W. Gao, Sun, H. - X., Xiao, H., Cui, G., Hillwig, M. L., Jackson, A., Wang, X., Shen, Y., Zhao, N., and Zhang, L., Combining metabolomics and transcriptomics to characterize tanshinone biosynthesis in Salvia miltiorrhiza, BMC genomics, vol. 15, no. 1, p. 73, 2014.
D. M. Hershey, Lu, X., Zi, J., and Peters, R. J., Functional conservation of the capacity for ent-kaurene biosynthesis and an associated operon in certain rhizobia, Journal of bacteriology, vol. 196, no. 1, pp. 100-106, 2014.
K. Potter, Criswell, J., Zi, J., Stubbs, A., and Peters, R. J., Novel Product Chemistry from Mechanistic Analysis of ent‐Copalyl Diphosphate Synthases from Plant Hormone Biosynthesis, Angewandte Chemie International Edition, vol. 53, pp. 7198-7202, 2014.
J. Zi, Mafu, S., and Peters, R. J., To Gibberellins and Beyond! Surveying the Evolution of (Di)Terpenoid Metabolism, Annual review of plant biology, vol. 65, pp. 259-286, 2014.
Q. Wang, Hillwig, M. L., Okada, K., Yamazaki, K., Wu, Y., Swaminathan, S., Yamane, H., and Peters, R. J., Characterization of CYP76M5–8 indicates metabolic plasticity within a plant biosynthetic gene cluster, Journal of Biological Chemistry, vol. 287, no. 9, pp. 6159-6168, 2012.
Q. Wang, Hillwig, M. L., Wu, Y., and Peters, R. J., CYP701A8: a rice ent-kaurene oxidase paralog diverted to more specialized diterpenoid metabolism, Plant physiology, vol. 158, no. 3, pp. 1418-1425, 2012.
L. Zu, Xu, M., Lodewyk, M. W., Cane, D. E., Peters, R. J., and Tantillo, D. J., Effect of isotopically sensitive branching on product distribution for pentalenene synthase: support for a mechanism predicted by quantum chemistry, Journal of the American Chemical Society, vol. 134, no. 28, pp. 11369-11371, 2012.
F. M. Mann, Xu, M., Davenport, E. K., and Peters, R. J., Functional characterization and evolution of the isotuberculosinol operon in Mycobacterium tuberculosis and related Mycobacteria, Frontiers in microbiology, vol. 3, 2012.
Y. Wu, Zhou, K., Toyomasu, T., Sugawara, C., Oku, M., Abe, S., Usui, M., Mitsuhashi, W., Chono, M., and Chandler, P. M., Functional characterization of wheat copalyl diphosphate synthases sheds light on the early evolution of labdane-related diterpenoid metabolism in the cereals, Phytochemistry, vol. 84, pp. 40-46, 2012.
K. Zhou, Xu, M., Tiernan, M., Xie, Q., Toyomasu, T., Sugawara, C., Oku, M., Usui, M., Mitsuhashi, W., and Chono, M., Functional characterization of wheat ent-kaurene(-like) synthases indicates continuing evolution of labdane-related diterpenoid metabolism in the cereals, Phytochemistry, vol. 84, pp. 47-55, 2012.
M. Xu, Galhano, R., Wiemann, P., Bueno, E., Tiernan, M., Wu, W., Chung, I. ‐M., Gershenzon, J., Tudzynski, B., and Sesma, A., Genetic evidence for natural product‐mediated plant–plant allelopathy in rice (Oryza sativa), New Phytologist, vol. 193, no. 3, pp. 570-575, 2012.
K. Zhou, Gao, Y., Hoy, J. A., Mann, F. M., Honzatko, R. B., and Peters, R. J., Insights into diterpene cyclization from structure of bifunctional abietadiene synthase from Abies grandis, Journal of Biological Chemistry, vol. 287, no. 9, pp. 6840-6850, 2012.
F. M. Mann and Peters, R. J., Isotuberculosinol: the unusual case of an immunomodulatory diterpenoid from Mycobacterium tuberculosis, Med. Chem. Commun., vol. 3, no. 8, pp. 899-904, 2012.
J. Criswell, Potter, K., Shephard, F., Beale, M. H., and Peters, R. J., A single residue change leads to a hydroxylated product from the class II diterpene cyclization catalyzed by abietadiene synthase, Organic letters, vol. 14, no. 23, pp. 5828-5831, 2012.
Y. Gao, Honzatko, R. B., and Peters, R. J., Terpenoid synthase structures: a so far incomplete view of complex catalysis, Natural product reports, vol. 29, no. 10, pp. 1153-1175, 2012.
Q. Wang, Hillwig, M. L., and Peters, R. J., CYP99A3: functional identification of a diterpene oxidase from the momilactone biosynthetic gene cluster in rice, The Plant Journal, vol. 65, no. 1, pp. 87-95, 2011.
M. L. Hillwig, Mann, F. M., and Peters, R. J., Diterpenoid biopolymers: new directions for renewable materials engineering, Biopolymers, vol. 95, no. 2, pp. 71-76, 2011.
M. L. Hillwig, Xu, M., Toyomasu, T., Tiernan, M. S., Wei, G., Cui, G., Huang, L., and Peters, R. J., Domain loss has independently occurred multiple times in plant terpene synthase evolution, The Plant Journal, vol. 68, no. 6, pp. 1051-1060, 2011.
K. Zhou and Peters, R. J., Electrostatic effects on (di)terpene synthase product outcome, Chemical Communications, vol. 47, no. 14, pp. 4074-4080, 2011.
D. Morrone, Hillwig, M., Mead, M., Lowry, L., Fulton, D., and Peters, R., Evident and latent plasticity across the rice diterpene synthase family with potential implications for the evolution of diterpenoid metabolism in the cereals, Biochem. J, vol. 435, pp. 589-595, 2011.
F. M. Mann, VanderVen, B. C., and Peters, R. J., Magnesium depletion triggers production of an immune modulating diterpenoid in Mycobacterium tuberculosis, Molecular microbiology, vol. 79, no. 6, pp. 1594-1601, 2011.
S. Mafu, Hillwig, M. L., and Peters, R. J., A Novel Labda‐7,13E‐dien‐15‐ol‐Producing Bifunctional Diterpene Synthase from Selaginella moellendorffii, ChemBioChem, vol. 12, no. 13, pp. 1984-1987, 2011.
Y. Wu, Hillwig, M. L., Wang, Q., and Peters, R. J., Parsing a multifunctional biosynthetic gene cluster from rice: Biochemical characterization of CYP71Z6 & 7, FEBS letters, vol. 585, no. 21, pp. 3446-3451, 2011.
F. M. Mann, Thomas, J. A., and Peters, R. J., Rv0989c encodes a novel (E)-geranyl diphosphate synthase facilitating decaprenyl diphosphate biosynthesis in Mycobacterium tuberculosis, FEBS letters, vol. 585, no. 3, pp. 549-554, 2011.
M. Köksal, Hu, H., Coates, R. M., Peters, R. J., and Christianson, D. W., Structure and mechanism of the diterpene cyclase ent-copalyl diphosphate synthase, Nature chemical biology, vol. 7, no. 7, pp. 431-433, 2011.