Publications

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Journal Article
A. Roy, Roberts, F. G., P Wilderman, R., Zhou, K., Peters, R. J., and Coates, R. M., 16-Aza-ent-beyerane and 16-Aza-ent-trachylobane: potent mechanism-based inhibitors of recombinant ent-kaurene synthase from Arabidopsis thaliana, Journal of the American Chemical Society, vol. 129, no. 41, pp. 12453-12460, 2007.
R. J. Peters, Flory, J. E., Jetter, R., Ravn, M. M., Lee, H. - J., Coates, R. M., and Croteau, R. B., Abietadiene synthase from grand fir (Abies grandis): characterization and mechanism of action of the “pseudomature” recombinant enzyme, Biochemistry, vol. 39, no. 50, pp. 15592-15602, 2000.
R. J. Peters, Ravn, M. M., Coates, R. M., and Croteau, R. B., Bifunctional abietadiene synthase: free diffusive transfer of the (+)-copalyl diphosphate intermediate between two distinct active sites, Journal of the American Chemical Society, vol. 123, no. 37, pp. 8974-8978, 2001.
F. M. Mann, Prisic, S., Hu, H., Xu, M., Coates, R. M., and Peters, R. J., Characterization and Inhibition of a Class II Diterpene Cyclase from Mycobacterium tuberculosis IMPLICATIONS FOR TUBERCULOSIS, Journal of Biological Chemistry, vol. 284, no. 35, pp. 23574-23579, 2009.
M. Xu, P Wilderman, R., Morrone, D., Xu, J., Roy, A., Margis-Pinheiro, M., Upadhyaya, N. M., Coates, R. M., and Peters, R. J., Functional characterization of the rice kaurene synthase-like gene family, Phytochemistry, vol. 68, no. 3, pp. 312-326, 2007.
M. Xu, Hillwig, M. L., Prisic, S., Coates, R. M., and Peters, R. J., Functional identification of rice syn‐copalyl diphosphate synthase and its role in initiating biosynthesis of diterpenoid phytoalexin/allelopathic natural products, The Plant Journal, vol. 39, no. 3, pp. 309-318, 2004.
R. P Wilderman, Xu, M., Jin, Y., Coates, R. M., and Peters, R. J., Identification of syn-pimara-7,15-diene synthase reveals functional clustering of terpene synthases involved in rice phytoalexin/allelochemical biosynthesis, Plant physiology, vol. 135, no. 4, pp. 2098-2105, 2004.
M. M. Ravn, Peters, R. J., Coates, R. M., and Croteau, R., Mechanism of abietadiene synthase catalysis: stereochemistry and stabilization of the cryptic pimarenyl carbocation intermediates, Journal of the American Chemical Society, vol. 124, no. 24, pp. 6998-7006, 2002.
S. Prisic, Xu, J., Coates, R. M., and Peters, R. J., Probing the role of the DXDD motif in class II diterpene cyclases, ChemBioChem, vol. 8, no. 8, pp. 869-874, 2007.
F. M. Mann, Prisic, S., Davenport, E. K., Determan, M. K., Coates, R. M., and Peters, R. J., A single residue switch for Mg2+-dependent inhibition characterizes plant class II diterpene cyclases from primary and secondary metabolism, Journal of Biological Chemistry, vol. 285, no. 27, pp. 20558-20563, 2010.
M. M. Ravn, Coates, R. M., Flory, J. E., Peters, R. J., and Croteau, R., Stereochemistry of the cyclization-rearrangement of (+)-copalyl diphosphate to (-)-abietadiene catalyzed by recombinant abietadiene synthase from Abies grandis, Organic letters, vol. 2, no. 5, pp. 573-576, 2000.
M. Köksal, Hu, H., Coates, R. M., Peters, R. J., and Christianson, D. W., Structure and mechanism of the diterpene cyclase ent-copalyl diphosphate synthase, Nature chemical biology, vol. 7, no. 7, pp. 431-433, 2011.
D. Morrone, Jin, Y., Xu, M., Choi, S. - Y., Coates, R. M., and Peters, R. J., An unexpected diterpene cyclase from rice: functional identification of a stemodene synthase, Archives of biochemistry and biophysics, vol. 448, no. 1, pp. 133-140, 2006.