Publications

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2012
F. M. Mann, Xu, M., Davenport, E. K., and Peters, R. J., “Functional characterization and evolution of the isotuberculosinol operon in Mycobacterium tuberculosis and related Mycobacteria”, Frontiers in microbiology, vol. 3, 2012.
K. Zhou, Gao, Y., Hoy, J. A., Mann, F. M., Honzatko, R. B., and Peters, R. J., “Insights into diterpene cyclization from structure of bifunctional abietadiene synthase from Abies grandis”, Journal of Biological Chemistry, vol. 287, no. 9, pp. 6840-6850, 2012.
F. M. Mann and Peters, R. J., “Isotuberculosinol: the unusual case of an immunomodulatory diterpenoid from Mycobacterium tuberculosis”, Med. Chem. Commun., vol. 3, no. 8, pp. 899-904, 2012.
2011
M. L. Hillwig, Mann, F. M., and Peters, R. J., “Diterpenoid biopolymers: new directions for renewable materials engineering”, Biopolymers, vol. 95, no. 2, pp. 71-76, 2011.
F. M. Mann, VanderVen, B. C., and Peters, R. J., “Magnesium depletion triggers production of an immune modulating diterpenoid in Mycobacterium tuberculosis”, Molecular microbiology, vol. 79, no. 6, pp. 1594-1601, 2011.
F. M. Mann, Thomas, J. A., and Peters, R. J., “Rv0989c encodes a novel (E)-geranyl diphosphate synthase facilitating decaprenyl diphosphate biosynthesis in Mycobacterium tuberculosis”, FEBS letters, vol. 585, no. 3, pp. 549-554, 2011.
2010
R. Cao, Zhang, Y., Mann, F. M., Huang, C., Mukkamala, D., Hudock, M. P., Mead, M. E., Prisic, S., Wang, K., and Lin, F. ‐Y., “Diterpene cyclases and the nature of the isoprene fold”, Proteins: Structure, Function, and Bioinformatics, vol. 78, no. 11, pp. 2417-2432, 2010.
F. M. Mann, Prisic, S., Davenport, E. K., Determan, M. K., Coates, R. M., and Peters, R. J., “A single residue switch for Mg2+-dependent inhibition characterizes plant class II diterpene cyclases from primary and secondary metabolism”, Journal of Biological Chemistry, vol. 285, no. 27, pp. 20558-20563, 2010.
N. Maugel, Mann, F. M., Hillwig, M. L., Peters, R. J., and Snider, B. B., “Synthesis of (±)-Nosyberkol (Isotuberculosinol, Revised Structure of Edaxadiene) and (±)-Tuberculosinol”, Organic letters, vol. 12, no. 11, pp. 2626-2629, 2010.
2009
F. M. Mann, Prisic, S., Hu, H., Xu, M., Coates, R. M., and Peters, R. J., “Characterization and Inhibition of a Class II Diterpene Cyclase from Mycobacterium tuberculosis IMPLICATIONS FOR TUBERCULOSIS”, Journal of Biological Chemistry, vol. 284, no. 35, pp. 23574-23579, 2009.
F. M. Mann, Xu, M., Chen, X., D Fulton, B., Russell, D. G., and Peters, R. J., “Edaxadiene: a new bioactive diterpene from Mycobacterium tuberculosis”, Journal of the American Chemical Society, vol. 131, no. 48, pp. 17526-17527, 2009.